Rotovap Conditions


These conditions can be improved upon, but they give a good starting point.

Solvent Bath Temp (° C) Vacuum (mm Hg) Time (min) % Recovery
Acetone 32 21 17 96
Ether 35 3 9 94
Ethanol 35 29 14 100
Ethyl Acetate 60 21 15 97
Hexanes 40 23 15 95
Methanol 30 26 30 100
Methylene Chloride 45-50 14 15 97
Petroleum Ether 35 13 15 90
THF 35 22 18 97
Toluene 50 29 6 96