Chemistry 438 » Spring » 2nd Half
2 Credits
Synthetic Design: Strategy and Tactics
Instructor(s): Robert K. Boeckman, Jr.Prerequisites: CHM 435.
Crosslisting: None.
Course Summary:
A formalism describing commonly employed strategies and tactics for the analysis of complex problems in organic synthesis will be presented. Examples of such strategies will be compared and contrasted during discussion of published complex molecule syntheses.
A formalism describing commonly employed strategies and tactics for the analysis of complex problems in organic synthesis will be presented. Examples of such strategies will be compared and contrasted during discussion of published complex molecule syntheses.
Course Topics:
- Guidelines for Retrosynthetic Analysis
- Examination/Evaluation/Comparison/Criticism of the Strategies/Tactics Employed in Selected Examples of Classical and Modern Syntheses of Stereochemically Complex Molecules from the Chemical Literature
Required Text:
The Logic of Chemical Synthesis, E.J. Corey and Xue-Min Cheng, New York: John Wiley & Sons, Inc. c1989.
Strongly recommended:
Organic Synthesis, the Disconnection Approach, Stuart G. Warren, Chichester-NewYork: Wiley c1982.
Reference texts:
Comprehensive organic transformations : a guide to functional group preparations, 2nd Ed., Richard C. Larock, New York : Wiley-VCH, c1999.
Organic Synthesis, Michael B. Smith, New York:McGraw-Hill, c2002.
The Logic of Chemical Synthesis, E.J. Corey and Xue-Min Cheng, New York: John Wiley & Sons, Inc. c1989.
Strongly recommended:
Organic Synthesis, the Disconnection Approach, Stuart G. Warren, Chichester-NewYork: Wiley c1982.
Reference texts:
Comprehensive organic transformations : a guide to functional group preparations, 2nd Ed., Richard C. Larock, New York : Wiley-VCH, c1999.
Organic Synthesis, Michael B. Smith, New York:McGraw-Hill, c2002.