Chemistry 422 » Fall » 1st Half
2 Credits
Nuclear Magnetic Resonance Spectroscopy
Instructor(s): Kara L. BrenPrerequisites: One year of organic chemistry and one semester of physical chemistry.
Crosslisting: None.
Course Summary:
This half-semester (2-credit) course will cover the fundamentals of nuclear magnetic resonance (NMR) spectroscopy. The physical basis for NMR will be described, as well as practical aspects of optimizing data collection, processing parameters, and interpretation of homonuclear and heteronuclear 1D and multidimensional spectra will be covered. Topics to be discussed include chemical shifts, relaxation, and exchange phenomena. Examples will draw from organic, inorganic, and biological chemistry. Exercises will include in-class discussions of NMR data in the literature.
This half-semester (2-credit) course will cover the fundamentals of nuclear magnetic resonance (NMR) spectroscopy. The physical basis for NMR will be described, as well as practical aspects of optimizing data collection, processing parameters, and interpretation of homonuclear and heteronuclear 1D and multidimensional spectra will be covered. Topics to be discussed include chemical shifts, relaxation, and exchange phenomena. Examples will draw from organic, inorganic, and biological chemistry. Exercises will include in-class discussions of NMR data in the literature.
Course Topics:
- Fundamentals of nuclear magnetization
- Causes and interpretation of the chemical shift
- Relaxation and line widths
- Scalar coupling (J values)
- Collection and processing of spectra
- Dipolar coupling and the nuclear Overhauser effect
- Multidimensional NMR
- NMR of chemically exchanging systems
Required Text:
NMR and Chemistry: An Introduction to Modern NMR Spectroscopy, by Akitt and Mann (ISBN 7487-4344-8)
NMR and Chemistry: An Introduction to Modern NMR Spectroscopy, by Akitt and Mann (ISBN 7487-4344-8)