Prerequisites: CHM 171 and CHM 173, coregistration in CHM 210. Crosslisting:None.
Course Summary: CHM 172 is a continuation of a one year exploration of the basic observations, concepts and practice of organic chemistry, with a focus on the fundamental relationships among molecular structure and chemical reactivity. The exploration will require that students grapple indepth issues: defining questions, evaluating evidence, weighing arguments, reflecting on epistemological issues, constructing new experiments, etc. The study of organic chemistry (focusing on chemical bonding, structure and stereochemistry, reactions and reaction mechanisms of organic compounds) will be carefully integrated with a review of the key concepts from general chemistry. Freshman Organic is designed for first year students with good preparation in chemistry (e.g., two years of general chemistry and an Advanced Placement score 4 or 5, or equivalent preparation). This sequence fast tracks students to more advanced chemistry courses and the fulfillment of degree requirements in other disciplines. Coregistration in CHM 210 (laboratory and lab/lecture) is required. There are lectures and one workshop per week. The workshop is an informal, interactive two-hour session in which small groups of students work on specially designed problems under the guidance of a trained leader. The purpose of the workshop is to provide a mechanism for students to work actively with the material and with each other. This course uses the Tuesday/Thursday 8:00 - 9:30 am Common Exam time.
The Robinson Annulation/ Michael Reaction â-Dicarbonyl Compounds/The Claisen Condensation
Carbonyl Chemistry/ Problem-Solving
The Mannich Reaction /Problem-Solving
Electrocyclizations and Cycloadditions
Strategies for Drug Development
Amino Acids and Proteins
Amino Acid Synthesis/ Protein Synthesis
Enzyme Chemistry/ Covalent Inhibition
Enzymes (Competitive Inhibition); Cofactors
Required Text: Organic Chemistry: Structure and Function, 6th Edition, K. Peter C. Vollhardt and Neil E. Schore
Guide: Study Guide and Solutions Manual for Organic Chemistry: Structure and Function, 6th Edition